コーホートプロファイル: 西中国病院連合の長期流行病学ウェルネス研究 (WHALE)
Yifei Lin1,2, Yong Yang3, Zhuyue Li3
1Health Management Center, General Practice Medical Center, Innovation Institute for Integration of Medicine and Engineering, West China Hospital, Sichuan University, Chengdu, Sichuan, China. ylin@wchscu.edu.cn.
European journal of epidemiology
|August 23, 2025
まとめ
ウェスト・チャイナ・ホスピタル・アライアンス (WHALE) 長期流行病学ウェルネス研究では,長期にわたる健康変化を追跡するために大規模なデータベースを使用しています. この研究は 予防的な医療のために 病気の発症に影響を与える要因の理解を深めるものです
科学分野:
- 流行病学
- 公衆衛生
- バイオメディカル・インフォマティック
背景:
- ウェスト・チャイナ・ホスピタル・アライアンス・ロングティチュードナル・エピデミオロジー・ウェルネス (WHALE) 研究は,健康から病気への移行に関する包括的なデータの必要性を解決するために設立されました.
- 遺伝的,行動的,環境的要因の相互作用を理解することは 積極的な医療の進歩に不可欠です
研究 の 目的:
- 健全で多面的なデータベースとコホートを作成し,健康の軌道を研究する.
- 健康から病気への移行に影響を与える要因の洞察を得るために
- バイオマーカーのデータ分析を通じて,老化,病前状態,疾患診断の理解を深める.
主な方法:
- WHALEデータベースは2010年に開始され,社会統計学,ライフスタイル,病歴,臨床情報を含む11の病院の健康診断データを統合しています.
- 2024年11月に開始されたWHALE Health Trajectory Cohortは,少なくとも3回の健康診断を行い,地域医療データベースとの積極的なフォローアップと受動的なリンクを使用する成人を採用しています.
- データ分析は,バイオマーカーデータ,経路パターン,および健康上の結果との関連に焦点を当てています.
主要な成果:
- 2025年1月現在,WHALEデータベースには1,526,686人の健康記録 (平均年齢は40.3歳,性別分布は均衡) が含まれています.
- 参加者の有意な割合 (23.88%) は少なくとも3回の健康診断を受け,3.31%は10回以上の健康診断を受けています.
- この研究は,バイオマーカーのパターンを老化,病前状態,診断された病気と結びつけ,健康の軌跡に関する重要な洞察を提供します.
結論:
- WHALEの研究の大きなサンプルサイズ,縦断的な設計,多様なデータ,品質管理は,疫学研究のための強力な基盤を提供します.
- この研究は,健康の軌跡や病気の発生に影響を与える要因について貴重な洞察を提供します.
- 将来の研究は,このリソースを活用して 積極的な医療戦略を推進し,複雑な疾患の病因に関する理解を深めることができます.
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