感情的ストレス:NHANESと中国のデータベースによって明らかにされた膀がんの発症と再発に関連した顕著な要因
Wentao Luo1, Yifei Chen1, Danjing Shen1
1Department of Urology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Annals of medicine
|August 23, 2025
まとめ
膀がん患者はうつ病のリスクが高くなります. 感情的ストレスも膀癌の再発に繋がり 精神的健康とこの病気の間の重要な関連を強調しています
科学分野:
- 腫瘍学
- 精神科
- エピデミオロジー
背景:
- 膀がんや感情的ストレスは 蔓延する健康問題です
- 膀がんと感情的ストレスとの関連に関する研究は,特に大きなサンプルサイズでは限られている.
研究 の 目的:
- 膀癌と感情的ストレスとの関連を調べるため
- 膀がんの発生とうつ病の関係を調べる
- 膀癌の再発と 感情的ストレスとの関係を調べるため
主な方法:
- 米国国立健康栄養検査調査 (NHANES) と上海第10人民病院の膀がんデータベースのデータを活用した.
- 2つの独立した横断研究を行いました.
- アソシエーションを分析するために多変数ロジスティック回帰を用いた.
主要な成果:
- NHANESのデータベースでは,膀がんと軽度のうつ病 (OR:2. 43,95%CI:1. 41,4. 00) の間に有意な正の関連性が見られた (n=23,801).
- 中国のデータベース (n=303) で,膀がんの再発と一般的なうつ病 (OR: 2.16, 95% CI: 1. 20, 3. 88) の間に有意な正の関連性が見られた.
結論:
- この研究は 膀がんと感情的ストレスが 密接に関連していることを示しています
- 膀がん患者はうつ病のリスクが大きい.
- 高い感情的ストレスは,膀がんの再発のリスクと関連している可能性があります.
関連する概念動画
Psychoneuroimmunology: Diabetes and Cancer
62
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
62
Stress and Mental Health
211
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
211
Psychoneuroimmunology: Cardiovascular Disease
78
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
78
Nursing Assessment of the Genitourinary System I: Health History
75
The genitourinary system is critical to maintaining fluid balance, waste elimination, and reproductive function. Nurses play a vital role in assessing this system, beginning with a thorough health history. This process involves gathering patient information, identifying risk factors, and recognizing symptoms of genitourinary disorders. Early detection is vital for timely interventions and management.1. Gathering Patient InformationA complete health history includes the patient’s personal,...
75
Psychological Responses to Stress
99
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
99
Introduction to Stress and Lifestyle
177
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
177


