代謝関連脂肪肝の患者におけるコレリチアシスの頻度と特徴
Yelyzaveta S Sirchak1, Dmitro O Dubovenko1, Mykhailo M Havrylec1
1UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE.
Wiadomosci lekarskie (Warsaw, Poland : 1960)
|August 23, 2025
まとめ
代謝関連脂肪肝疾患 (MAFLD) の患者の36. 1%に罹患しています. MAFLD患者における肥満の進行は,小胆石のサイズと相関し,臨床表現に影響する.
科学分野:
- ヘパトロジー
- 胃腸内科
- 医療診断
背景:
- 代謝関連脂肪肝 (MAFLD) は健康上の懸念が高まっている.
- 胆管疾患 (GD) は,MAFLD患者の共同疾患である.
- MAFLDにおける体量指数 (BMI) とGD特性の関係については,さらなる解明が必要である.
研究 の 目的:
- メタボリック関連脂肪肝疾患 (MAFLD) の患者における胆囊疾患 (GD) の頻度を決定する.
- ボディ・マス・インデックス (BMI) に基づいて,MAFLD患者におけるGDの臨床経過の特異性を調査する.
主な方法:
- MAFLDと診断された324人の患者群を調査した.
- 胃腔の超音波検査を用いて,胆管の状態を評価した.
- 患者は,GDの存在または欠如に基づいてグループに分類され,BMIによって分類されました.
主要な成果:
- 胆囊病 (GD) は,MAFLD患者の36. 1% (124人中117人) で確認された.
- 2度目の肥満のMAFLD患者は,主により大きな胆石 (> 10. 0mm) を示した.
- 体重指数 (BMI) が正常または過体重の患者は,より小さな胆石 (≤5. 0mm) の有病率が高かった.
結論:
- 代謝関連脂肪肝疾患 (MAFLD) の患者の36. 1%に Gallbladder disease (GD) が流行している.
- MAFLD患者における肥満の進行と胆石の大きさの間には逆の関係がある.
- BMIは,MAFLDにおける胆石の特徴に影響を与える重要な要因です.
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