関連する実験動画

Updated: Sep 10, 2025

Author Spotlight: Optimizing CFPS Systems for Synthetic Cell Construction
07:43

Author Spotlight: Optimizing CFPS Systems for Synthetic Cell Construction

Published on: April 19, 2024

3.2K

合成ポルフィリンアセンブリと生成タンパク質設計の統合:バイポルフィリン取得設計タンパク質の金属反応性サイクルアセンブリ

Hiroaki Inaba1, Hiroki Onoda2, Takayuki Uchihashi3,4,5

  • 1Department of Chemistry, School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi, 464-0802, Japan.

Small (Weinheim an der Bergstrasse, Germany)
|August 23, 2025
PubMed
まとめ

研究者らは新型の人工タンパク質アセンブリであるBi-Porphyrin Acquisition Designer (BiPAD) を開発し,合成超分子設計と新しいタンパク質工学を統合した. このタンパク質組成は合成ポルフィリンを正確に捕捉し,金属反応性サイクル構造を形成し,機能的なシステムの設計のための新しい道を開きます.

キーワード:
新しいタンパク質ポルフィリノイドタンパク質の設計自己組み立て超分子化学

さらに関連する動画

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.4K
Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer09:37

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Published on: April 27, 2020

11.2K

関連する概念動画

Synthetic Biology02:55

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.0K
Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
10.8K
Structure of Porins01:21

Structure of Porins

Mitochondria, chloroplasts, and gram-negative bacteria have transmembrane, beta-barrel proteins called porins to mediate the free diffusion of ions and metabolites across the membrane. Mitochondrial porin precursors contain conserved amino acid sequences called beta signals at their C-terminal. Beta signals have a  motif of PoXGXXHyXHy (Po-Polar, X-Any amino acid, G-Glycine, Hy-LargeHydrophobic), which are crucial for precursor recognition to initiate precursor assembly. Beta-barrel...
3.2K
Porin Insertion in the Outer Mitochondrial Membrane01:12

Porin Insertion in the Outer Mitochondrial Membrane

Porins are beta-barrel proteins translocated to the mitochondrial outer membrane through the TOM complex into the intermembrane space. Porin precursors bind TIM chaperones within the intermembrane space and are guided to the Sorting and Assembly Machinery complex or SAM complex on the outer mitochondrial membrane.
Three models describe the assembly of porins by the SAM complex and their insertion into the outer membrane. Model 1 suggests that porins are assembled outside the SAM channel as the...
3.3K