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Updated: Sep 10, 2025

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制御された衰弱パラメータによる代謝,心血管,肝臓の健康の予測:予防的肝臓病学者の潜在的なスクリーニングツール

Ajay Kumar Mishra1

  • 1Department of Hepatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Hepatology research : the official journal of the Japan Society of Hepatology
|August 23, 2025
PubMed
まとめ

No abstract available in PubMed .

キーワード:
MASLD についてNAFLD制御された減衰パラメータ肝臓の健康について

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Drug transporters are critical in drug absorption, distribution, and excretion processes. They should be included in physiological-based pharmacokinetic (PBPK) models, which help predict human drug disposition. However, predicting this is challenging during drug development, especially when liver transport is involved. However, with a realistic representation of body transport processes, an accurate model may be possible.
A recent model describes pravastatin's hepatobiliary excretion,...
79
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