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Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
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Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
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An Overview of Psychoactive Drugs01:28

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Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
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クラシックサイケデリックの使用による急性効果と長期的な神経心理学的結果

Lukas Andreas Basedow1, Thomas Günther Riemer2

  • 1Department of Psychology, Clinical Psychology and Psychotherapy, Philipps-Universität Marburg, Marburg, Germany. lukas.basedow@uni-marburg.de.

Current topics in behavioral neurosciences
|August 23, 2025
PubMed
まとめ

サイケデリックの使用は 一時的に注意力や記憶などの 認知機能を損なうので 特定の状況でリスクが生じます しかし,繰り返し使用すると,神経心理学的持続的な害は生じません.

キーワード:
認知能力ハルシノゲン害の軽減神経心理学

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科学分野:

  • 神経科学
  • 心理学

背景:

  • サイケデリック薬は 精神疾患の治療の可能性を 探求している.
  • これらの物質のレクリエーション利用も増加しています.
  • サイケデリックの使用の認知および神経心理学的影響に関する懸念があります.

研究 の 目的:

  • サイケデリックの使用の急性,亜急性,および長期的な神経心理学的影響を調査する.
  • サイケデリック物質の潜在的害を分析する.

主な方法:

  • サイケデリックの使用中のおよび後の神経心理学的パフォーマンスを調べた研究のレビュー.

主要な成果:

  • サイケデリックの使用は神経心理学的機能,特に注意力と作業記憶を急激に低下させます.
  • これらの急性障害は通常,使用後1日以内に治る.
  • 実行機能の障害は使用後最大24時間持続する可能性があります.
  • 繰り返されたサイケデリックの使用は,持続的な神経心理学的欠陥を誘導するものではありません.

結論:

  • サイケデリックの使用中および24時間以内には,一時的な認知障害による注意が必要です.
  • 現在の証拠によると サイケデリックは 繰り返し使用することで 直接的な長期的な神経心理的被害を 引き起こしません
  • 特定の物質の効果と慢性的な使用の影響に関するさらなる研究が必要である.