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Updated: May 4, 2026

Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia
10:13

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Published on: July 31, 2017

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クリソファノールはNRF2/ARE/GSDMDシグナル伝達経路を調節することにより,イシュケミア/再注射誘発のニューロン炎症を抑制する

Feijian Zeng1, Yao Liang2, Yufei Wei1

  • 1Section 2, Department of Encephalopathy, First Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi 530023, China.

Tissue & cell
|August 23, 2025
PubMed
まとめ

クリソファノール (CHR) は脳卒中後の損傷から脳細胞を保護し,炎症と細胞死亡を軽減します. NRF2経路を活性化させ,ニューロンの炎症を予防し,脳性缺血/再注射損傷の新たな治療法を提供することができる.

キーワード:
脳のI/R損傷クリソファノールGSDMD についてNRF2 についてピロプトーシス

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