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Updated: Sep 10, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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ビスフェノールAは,miRNA-449a媒介によるSIRT1によるSW1353コンドロサイトにおける細胞老化を誘導する

Yu Gui1, Cun Li1, Wenrui Wang1

  • 1Department of Environmental Health, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, PR China; Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention (China Medical University), Ministry of Education, PR China.

Ecotoxicology and environmental safety
|August 23, 2025
PubMed
まとめ

ビスフェノールA (BPA) 曝露は,マイクロRNA-449aを通じてSIRT1をダウンレギュレーションすることによって,コンドロサイト老化を誘発する. この分子メカニズムは BPAが軟骨の健康を 破壊し 病気に寄与する方法を示しています

キーワード:
ビスフェノールA細胞の老化ミRNA-449aSW1353 についてシルトゥイン 1

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