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Updated: Sep 10, 2025

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NMRを大型RNAに適用する

Brian D Grossman1, Jan Marchant1, Michael F Summers1

  • 1Howard Hughes Medical Institute and Department of Chemistry and Biochemistry, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.

Journal of molecular biology
|August 23, 2025
PubMed
まとめ

新しい核磁共振 (NMR) 方法は,大きなRNAの原子レベルの構造研究を可能にします. これらの高度な技術は,従来のNMRの限界を克服し,複雑なRNA構造の分子分析の範囲を広げています.

キーワード:
NMR についてRNA についてダイナミクスイソトープのラベル付けマクロ分子構造

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Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
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