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Updated: Sep 10, 2025

Activating Autophagy by Aerobic Exercise in Mice
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Activating Autophagy by Aerobic Exercise in Mice

Published on: February 3, 2017

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ACAA1 ノックアウトは,オートファギーを活性化することによって,KPCマウスの生存率を増加させる

Ho Lee1, Mingyu Kang2, Sung Hoon Sim3

  • 1Division of Cancer Biology, Research Institute, National Cancer Center, Goyang, Republic of Korea; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Republic of Korea.

Molecular metabolism
|August 23, 2025
PubMed
まとめ

臓管腺がん (PDAC) のアセチル共酵素Aアシルトランスファーゼ1 (ACAA1) を標的として,オートファギーを誘導することによって腫瘍の成長を抑制する. このアプローチは,正常なエネルギー代謝を害することなく,癌細胞の成長を特に阻害します.

キーワード:
ACAA1 についてオートファジー脂肪酸の酸化臓がんペロキシソーム

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