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Updated: Sep 10, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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がん細胞におけるYY1-EZH2-RKIP軸の異常と免疫回避

Talia Festekdjian1, Benjamin Bonavida1

  • 1Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, CA 90095, USA.

Biochimica et biophysica acta. Reviews on cancer
|August 23, 2025
PubMed
まとめ

YY1- EZH2- RKIP軸をターゲットにすることで,がんの免疫療法に対する抵抗を克服することができます. この軸は免疫回避を調節し,その抑制は反応しない患者の抗腫瘍反応を回復させる可能性があります.

キーワード:
癌についてクロス・トークEZH2 について免疫回避RKIP治療的なターゲティングYY1 について

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