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Updated: Sep 10, 2025

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
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Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue

Published on: February 24, 2023

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リウマチ性関節炎のシナヴィアルニッチの空間的なマッピングは,治療への反応に関連したLYVE1+マクロファージネットワークを明らかにします

Julien De Lima1, Marie-Astrid Boutet2, Olivier Bortolotti3

  • 1Nantes Université, ONIRIS, CHU Nantes, INSERM, Regenerative Medicine and Skeleton, RMeS, Nantes, France.

Annals of the rheumatic diseases
|August 23, 2025
PubMed
まとめ

シノビウム内の特定のマクロファージネットワークの回復は,従来の合成疾患修正抗レウマティック薬 (csDMARDs) で,関節リウマチ (RA) の寛解の鍵です. この発見は,RA治療の新たな治療目標を示しています.

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