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Updated: Sep 10, 2025

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
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Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption

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DCTPP1は,AUF1経由で,ヒトの小性トロフォブラストにおける酸化ストレスホメオスタシスを調節する

Yajuan Lu1, Xue Wu1, Lei He1

  • 1Institute of Reproductive Medicine, Medical School, Nantong University, Nantong, Jiangsu, China.

Cell death discovery
|August 23, 2025
PubMed
まとめ

胎盤細胞におけるデオキシチジントリフォスファートパイロファタゼ1 (DCTPP1) の発現が低下すると,酸化ストレスとアポトーシスが増加し,妊娠中絶 (MA) に寄与する. DCTPP1とAUに富んだ元素RNA結合タンパク質1 (AUF1) の相互作用が鍵となる.

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A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta11:44

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

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