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Updated: Sep 10, 2025

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates

Published on: August 21, 2018

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硫黄またはセレニウムで改変された尿素は,tRNA機能のためのU-G振動ペアの物質である

Katarzyna Kulik1, Barbara Nawrot1

  • 1Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363, Lodz, Poland.

Current medicinal chemistry
|August 24, 2025
PubMed
まとめ

tRNAの振動位置における硫黄とセレニウムの改変は遺伝子発現に不可欠である. これらの改変は,塩基配列とコドン解読に影響することで,翻訳の精度と効率を調整します.

キーワード:
2-セレノウリジン2-チオウリジンカルコゲンセレニウム硫黄tRNAの改変トランスファーリボ核酸振動する位置

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