[懸念の表れ]マイクロRNA‐183‐5pのダウンレギュレーションは,レチキュロカルビン‐2/Wnt/β‐カテニンのシグナル伝達経路を無効化することによって,大腸がん細胞の増殖と侵入を抑制する.
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PubMedで要約を見る
まとめ
この要約は機械生成です。トランスウェル解析実験の潜在的データ重複に関する懸念が提起され,特にフィグ. 3Hと4Cで 編集部では データの重複を理由に 科学的整合性を調査しています
科学分野
- 分子生物学
- バイオメディカル 研究
背景
- 公開された研究で 潜在的に重複するデータに関する懸念が指摘された.
- 図に示されたトランスウェル測定実験で指摘された特定の問題. 3と4で
研究 の 目的
- 実験データプレゼンテーションの読者によって特定された異常に対処する.
- 出版された論文の科学的な完全性に関する潜在的な問題を調査する.
主な方法
- 図で示されたデータの見直し 3Hと4Cで
- データの重複を明らかにするために著者と連絡する.
- 編集部が科学的な誠実さについて調査している.
主要な成果
- Fig.の"Invasion/NC"パネルの間に明らかに重なり合っているデータセクション. 3H と Fig. 4C について
- 異なる実験を示唆するデータは,同一のオリジナルソースを使用している可能性があります.
- 著者は編集部の問い合わせにまだ答えていません.
結論
- 懸念の表れは,科学的誠実さの潜在的な問題のために発行されます.
- 編集部はこの件について調査を続けている.
- 読者は,さらなる調査を待っている潜在的な問題について通知されます.
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