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トリガー日に卵泡の直径に基づいて採取された最小卵子の数を推定できますか? コホート研究

Julia K Bosdou¹, Christos A Venetis¹, Leonidas Zepiridis¹

¹Unit for Human Reproduction, 1st Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Reproductive biomedicine online

|August 24, 2025

まとめ

発症した日の葉っぱの直径はIVFで卵細胞の回収を予測することができます. 卵泡の直径16mmは100%の卵細胞回収率を示し,臨床的決定に役立ちます.

科学分野:

生殖医学
試管受精 (IVF)
卵巣刺激

背景:

IVF 治療の有効な計画には,卵細胞の精確な予測が不可欠です.
卵泡の大きさは卵細胞の成熟度と潜在的回収率の重要な指標です.

研究の目的:

卵泡の直径が最終熟成のトリガーであるかどうかを判断するには,IVFで回収された最小の卵細胞数を推定することができます.
卵巣の大きさに基づいて卵細胞回収の予測モデルを確立する.

主な方法:

330人の患者から429回のIVFサイクルを観察したコホート研究.
トリガー日に卵胞直径 (11-24mm) 単位で計算した卵細胞回収率.
卵巣採取率の 95% の信頼区間が 100% に達した最小の卵泡直径を決定した.

主要な成果:

トリガー日16mmの卵泡直径は,100%の卵細胞回収率 (IC95%以下) と関連付けられました.
18mmの直径は,成熟した (MII) 卵細胞の回収を予測し,中位率は133. 3% (95%CI 112.5 - 154. 2%) であった.
採取された卵子細胞の平均値は5. 0で,成熟卵子細胞は4. 0でした.

結論:

トリガー日に卵泡の直径を測定すると,卵細胞の採取量を推定する信頼できる方法が得られます.
この予測能力は患者のカウンセリング,臨床的意思決定,そしてIVFに対する実験室の準備を高めることができます.
この発見は,正確な卵泡のサイズ評価を通じて,IVFプロトコルを最適化することを支持しています.

キーワード:

葉っぱの直径ゴナドトロフィン放出ホルモンのアゴニスト卵細胞回収率卵細胞リコンビネントヒトコリアン・ゴナドトロフィン

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