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Updated: Sep 10, 2025

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
09:49

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Published on: July 5, 2019

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癌の進行におけるNRG1融合グリコプロテイン - 構造的メカニズムと治療の可能性:レビュー

Zhe Wang1, Huike Wang2, Bohan Zhao3

  • 1Department of Oncology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou, Henan 450052, China; Henan Key Laboratory of Chronic Disease Prevention and Therapy & Intelligent Health Management, No. 1 Jianshe East Road, Zhengzhou, Henan 450052, China.

International journal of biological macromolecules
|August 24, 2025
PubMed
まとめ

ニューレグルリン1 (NRG1) 融合は,ErbB2 / ErbB3信号をハイジャックし,腫瘍の成長と治療抵抗を促進する珍しい腫瘍誘発因子です. このレビューは,精密腫瘍学のNRG1融合生物学と治療戦略をまとめています.

キーワード:
ErbB受容体複合体フュージョン・グリコタンパク質ニューレグリン 1

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