術前の阻害性睡眠無呼吸症候群と,一般的な手術を受ける患者の間での長期間のオペオイド使用との関連
PubMedで要約を見る
まとめ
この要約は機械生成です。手術後のオピオイドの長期使用とは関係ありません. この研究では関連性が見出されず,手術後の長期オピオイド使用の変更可能な危険因子ではないことを示唆しています.
科学分野
- 医学研究
- 臨床的結果
- 医療情報学
背景
- 手術後の長期オピオイド使用を減らすには 患者のリスク要因を特定することが重要です
- 阻害性睡眠無呼吸 (OSA) は潜在的な危険因子として提案されていますが,長期にわたるオピオイド使用との関連は不明です.
研究 の 目的
- 術前阻害性睡眠無呼吸 (OSA) の診断と長期間の術後オピオイド使用との関連を調査する.
- 手術後の長期オピオイド摂取に 影響する変化可能なリスク因子であるかどうかを判断する.
主な方法
- MarketScan CommercialとMedicare Claims Database (2016-2021) から利用された医療保険請求の管理データです.
- オピオイド未使用の患者で,11件の一般的な手術を受けた.
- ICD-10のコードで定義された手術前OSAおよび手術後の長期オピオイド使用は,手術後91~365日以内に≥10回の処方箋または≥120日間の供給として,多変数ロジスティック回帰で分析されました.
主要な成果
- 270,320人の患者が含まれており,10. 8%が手術前OSAと診断された.
- 多変量調整後,手術後の長期オピオイド使用の発生率はOSAとOSA以外のグループで0. 4%であった (p=0. 184).
- 結果は様々な分析仕様で一致した.
結論
- 手術前におけるOSAの診断は,長期間のオピオイド使用のリスク増加と関連しませんでした.
- 発見は,OSAは,一般の手術用集団における長期間のオピオイド使用の変更可能な危険因子ではないことを示唆しています.
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