フランス総合がん治療センターの専用救急治療室に通っている患者の緩和ケアへの系統的な紹介:将来的な多センターランダム化比較臨床試験 PALLU
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PubMedで要約を見る
まとめ
この要約は機械生成です。早期の緩和ケアへの紹介は 癌患者の生命の末期における 積極的な治療を減少させます この研究は,治療の質と患者の成果を改善することを目的として,体系的な紹介と標準的な紹介を比較しました.
科学分野
- 腫瘍学
- 緩和ケア
- 臨床試験
背景
- 国際的なガイドラインでは,がん患者の症状管理と生活の質の向上のために,早期の緩和ケア統合を推奨しています.
- 制御不能な症状は緩和ケアへの紹介の重要な指標であり,緊急治療室への訪問の一般的な理由です.
- 北米の以前の研究では 救急医療施設からの緩和医療の紹介は 実現可能で効果的であると示唆されています
研究 の 目的
- 緊急時における 早期の緩和医療の推薦が 医療チームの要請による推薦と比較して 積極的な終末期ケアを減少させるかどうかを 判断する.
- 終末期に積極的な治療を受けている患者の割合を 系統的および標準的な紹介グループで比較する.
主な方法
- PALLIA-10スコアが3以上で,フランスの総合がんセンターの予定外の診察に参加した患者を対象とした多中心的ランダム化比較試験.
- 患者はランダムに (1: 1) 系統的緩和ケア (実験群) または医療腫瘍学チームの要求による紹介 (標準群) に割り当てられました.
- 主要エンドポイント: 積極的な終末期ケアのための少なくとも1つの基準を満たす患者の割合 サンプルサイズ:中退を考慮する患者240人
主要な成果
- この研究は,体系的な紹介グループにおいて,ケアに対する攻撃性の20%の減少 (65%から45%) を検出することを目的としています.
- 副次的な目的は,介護の積極性,緩和ケアの必要性,患者の報告された結果,死亡場所,および全生存率の分析です.
- 保健経済学と人文/社会科学の学科も紹介されます.
結論
- この研究は,緊急事態に対応するがん患者に対する 緩和ケア統合の最適なタイミングと有効性に関する重要なデータを提供します.
- 研究結果は,臨床実践のガイドラインを導き,がん患者の終末期ケアを改善する見込みです.
- 成果は国際学術誌で公表される.
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