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Updated: Sep 10, 2025

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation

Published on: January 19, 2019

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薬剤誘発の可塑性下での抗がん治療の最適な用量

Einar Bjarki Gunnarsson1,2, Benedikt Vilji Magnússon3, Jasmine Foo4

  • 1Division of Applied Mathematics, Science Institute, University of Iceland, Reykjavik, Iceland. ebg@hi.is.

NPJ systems biology and applications
|August 24, 2025
PubMed
まとめ

この研究は,がんの最適な治療には,非遺伝的薬剤耐性を管理することによって,細胞破壊と抵抗のバランスをとることが含まれていることを明らかにしています. 絶え間ない低用量または断続的な高用量による最良の投与戦略は,細胞がどれだけ早く耐性になるかに依存します.

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