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Updated: Sep 10, 2025

Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells
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Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells

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ビクロンガンモパシーをシミュレートするポリメリ化IgAモノクローナルガンモパシー:事例報告

Kadija Mefire1, Ouissam El Mohtarim1, Samira El Machtani Idrissi1

  • 1Biochemistry-Toxicology Laboratory, Faculty of Medicine and Pharmacy, Mohammed V Military Training Hospital, Mohammed V University, Rabat, MAR.

Cureus
|August 25, 2025
PubMed
まとめ

血清タンパク質電解の2つのモノクローナル帯は,バイクローナルガンモパシーを示す可能性があります. しかし,このケースは,IgAラムダが複数のポリマーを形成し,バイクローナリティを模倣することを示しています. ベータ・メルカプトエタノールは単一の単一のIgAラムダ成分を確認した.

キーワード:
バイクローナルガンモパシー毛細血管電解モノクローンガンモパシーパラタンパク質ポリマー免疫グロビンA

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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation09:02

Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation

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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study11:10

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
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