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Updated: Sep 10, 2025

Osteoclast Derivation from Mouse Bone Marrow
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PPARα活性化によって骨格形成と骨の喪失を促進する

Laimar C Garmo1, Mackenzie K Herroon1, Shane Mecca1

  • 1Department of Pharmacology, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI, United States.

Toxicology reports
|August 25, 2025
PubMed
まとめ

ペルおよびポリフルオアルキル物質 (PFAS) は,骨のミネラル密度を低下させ,骨の分解を促進することで,骨の健康を害します. 研究によると,マウスのGenXとPFHxSへの曝露により,骨が薄くなり,組成が変化しました.

キーワード:
BMD について骨のミネラル密度オステオクラストゲネシスPFAS についてPFASの毒性についてPPAR についてペルおよびポリフルオアルキル物質

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