ビタミンD欠乏症と肩手術後の有害事象との関連: 系統的レビューとメタ解析

Dimitrios V Papadopoulos¹, Athanasios Kontogiannis¹, Nikolaos Stavropoulos¹

¹Second Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Indian journal of orthopaedics

|August 25, 2025

まとめ

ビタミンD欠乏症は,肩の手術や全肩関節整形手術など,肩の手術後の有害事象のリスクを高めます. ビタミンDのレベルが低い患者は合併症のリスクが1.2倍高いのです

科学分野:

整形外科
栄養学
術後のケア

背景:

ビタミンD欠乏症は整形外科で懸念される問題です
手術後の結果,特に肩の手術後の影響は徹底的な調査が必要である.

研究の目的:

ローターカフ (RCR) 修復や肩関節整形手術 (TSA) の後に,ビタミンD欠乏が有害事象の増加と関連しているかどうかを判断する.

主な方法:

観察コホートとケース・コントロール研究の体系的なレビューとメタ分析.
2023年5月まで発表された研究をPubMedとSCOPUSのデータベースで検索した.
再発症や再手術を含む有害事象に対して,プールされた確率比 (OR) と95%信頼区間 (CI) を計算した.

主要な成果:

41,000人を超える被験者を含む4つの研究が含まれた.
ビタミンD欠乏症の患者は,RCRまたはTSA後の有害事象の発生率が1. 23倍高かった (OR: 1.23,95%CI: 1. 14~1. 34,p < 0. 001).
RCRのサブグループ分析では,ビタミンD欠乏症患者における有害事象の確率は1. 19倍であった (OR: 1. 19,95%CI: 1. 09-1.29,p = 0. 019).

結論:

ビタミンD欠乏症は,RCRとTSA後の有害事象の発生率が高いと関連しています.
この関連性の病理生理学を明らかにするためにさらなる研究が必要である.

キーワード:

改造手術ローターカフの修理肩の手術の合併症肩関節整形手術ビタミンD欠乏症

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