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Updated: Sep 10, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
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自己免疫疾患:遺伝的易感性,環境的トリガー,免疫機能障害 治療法をどこで開発できるのか?

Manoj Kumar1,2, Linda Yip1, Fangyuan Wang1

  • 1Department of Medicine, School of Medicine, Stanford University, Palo Alto, CA, United States.

Frontiers in immunology
|August 25, 2025
PubMed
まとめ

自己免疫疾患は 免疫調節を妨げる 遺伝的および環境的要因に起因します 新しい治療法はインタールイキン2受容体 (IL-2R) のシグナル伝達を標的とし,T細胞の調節機能と免疫耐性を回復させます.

キーワード:
自己免疫疾患グライルIL-2受容体のシグナル伝達環境 トリガー遺伝的感受性ネドリレーションリン-S6規制T細胞

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