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Updated: Sep 10, 2025

A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection
09:15

A Mouse Model to Assess Innate Immune Response to Staphylococcus aureus Infection

Published on: February 28, 2019

11.9K

CCL20/CCR6シグナリングは,骨髄炎の確立中に疾患の重症度を調節する

Himanshu Meghwani1, Javier Rangel-Moreno2, Kyra M Sandercock1

  • 1Department of Orthopedics, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.

mBio
|August 25, 2025
PubMed
まとめ

CCL20/CCR6軸は,Staphylococcus aureus骨髄炎に対する免疫防御に不可欠である. この経路を遮断すると,骨の感染が悪化し,T細胞の増殖が妨げられ,CCL20がセプシスのバイオマーカーとなる.

キーワード:
CCL20 についてCCR6 についてスタフィロコッカス・オーレウスT細胞ホストの免疫骨髄炎

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