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Updated: Sep 10, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
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皮膚 メラノーマ の 概要

Urvashi Mitbander Joshi1,2, Mohammed Kashani-Sabet3, John M Kirkwood1

  • 1University of Pittsburgh Medical Center, Hillman Cancer Center, Pittsburgh, Pennsylvania.

JAMA
|August 25, 2025
PubMed
まとめ

メラノーマの発生率は上昇していますが,初期段階の疾患 (IA-IIA) は手術で治療されています. 進行性メラノーマ (IIB- IV) は,免疫療法 (抗PD-1,イピリムマブ,ニボルマブ) と標的療法 (BRAF+MEK阻害剤) によって生存率が改善された.

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