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Updated: Sep 10, 2025

Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
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Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.

Published on: February 15, 2019

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ガルシニア・マルチフロラからの新型ビフェニル: 隔離およびα-アミラーゼ阻害性

Li Hua Gong1, Si Yi Wei2, Zhi Lin Jiao1

  • 1The Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang, P. R. China.

Chemistry & biodiversity
|August 25, 2025
PubMed
まとめ

ガルシニア・マルチフローラの茎と葉は 7つのビフェニル化合物,4つの新しい化合物を生み出しました これらの化合物はアルファアミラーゼに強い結合を示したが,インビトロでは弱い酵素抑制活性を示したものは2つだけであった.

キーワード:
ガーシニア・マルチフロラビフェニル化合物酵素抑制活動分子ドッキングα-アミラーゼ

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Oral Hypoglycemic Agents: α-Glucosidase Inhibitors01:19

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...
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Dipeptidyl Peptidase 4 Inhibitors01:23

Dipeptidyl Peptidase 4 Inhibitors

Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a...
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