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Updated: Sep 10, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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転移性がん患者の遺伝的傾向のためのeHealth配信の代替方法:ランダム化試験のためのプロトコル

Kimberley T Lee1,2, Briana McLeod1, Brian Egleston3

  • 1Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

JMIR research protocols
|August 25, 2025
PubMed
まとめ

eREACH研究では,転移したがん患者の遺伝子検査のためのデジタル介入をテストし,アクセスと結果を改善することを目指しました. 結果は待っていますが このアプローチにより 遺伝子検査のアクセシビリティが 拡大する可能性があります

キーワード:
デジタル・ヘルス遺伝子カウンセリング遺伝子検査転移した癌,デジタル遺伝子教育

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Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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