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Updated: May 2, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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Published on: January 11, 2020

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アルツハイマー病や認知症と診断されていない人のためのデジタルツール: スコップレビュー

Tanja J de Rijke1,2,3,4,5, Thomas Engelsma5,6, Chi Him Ng6

  • 1Department of Medical Psychology, Amsterdam University Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands, 31 205663622.

Journal of medical Internet research
|August 25, 2025
PubMed
まとめ

アルツハイマー病 (AD) の予防のためのデジタルツールは有望ですが,さらなる開発が必要です. ほとんどのツールは初期段階にあり 認知機能低下を効果的に管理するには より多くの研究と政策の変更が必要です

キーワード:
脳の健康デジタルツール多様性eヘルス電子医療イクティブ将来の方向性影響評価実施m ヘルス移動医療成期段階

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The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living08:36

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
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Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and...
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