聴覚障害の発症後の認知症のリスク:全国的なコホート研究
Arad Kodesh1, Riki Taitelbaum-Swead2, Hannah Kuper3
1Department of Community Mental Health, University of Haifa, Haifa, Israel; Mental Health Department, Meuhedet Health Services, Tel Aviv, Israel.
Journal of the American Medical Directors Association
|August 25, 2025
まとめ
発症したばかりの聴覚障害は 認知症のリスクを大幅に高めます 早期のモニタリングや 補聴器などの介入は このリスクを軽減するのに役立ちます
科学分野:
- 神経科学
- 流行病学について
- ゲロントロジー
背景:
- 聴覚障害と認知症のリスクに関する以前の研究は不一致です.
- 以前の研究における潜在的なバイアスは未検証であり,さらなる調査が必要である.
研究 の 目的:
- 全因性聴覚障害の発症と認知症発症のリスクとの関連を調査する.
- 聴覚障害と認知症に関する既存の文献の不一致と潜在的なバイアスに対処する.
主な方法:
- イスラエル の 健康 維持 機関 の 51 歳 から 71 歳 の 102,067 人 の 参加 者 を 対象 と し た 全国 コーホート 研究.
- 聴覚障害を時間的に変化する共変数として,発生性認知症の追跡期間は最大17. 2年.
- 20の混同因子で調整された逆確率の重みを持つコックス回帰モデルが認知症リスクを評価するために使用されました.
主要な成果:
- 聴覚障害の発症は,全因性認知症のほぼ2倍リスクと統計的に有意に関連していた (調整HR,1. 91).
- 認知症の発生率は,聴覚障害のある個体では8. 9%で,聴覚障害のない個体では4. 11%であった.
- 補足的な分析は,補聴器の使用が認知症のリスクを減らす可能性があることを示し,一部は中程度の逆因果関係を示唆した.
結論:
- 聴覚障害の発生は認知症の危険性が高くなります
- 聴覚障害のモニタリングは 認知症予防戦略の実施に不可欠です
- 助聴器や助聴器の使用は 認知症の予防に役立っています
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