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Updated: Sep 10, 2025

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology
09:12

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology

Published on: May 3, 2021

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SGLT1/2の選択性を誘発する空間的および電子的特徴:分子動力学と量子力学の組み合わせ研究

Bingkun Chen1,2,3, Baichun Hu1,2,4, Yuxiang Zong1,2,4

  • 1Key Laboratory of Intelligent Drug Design and New Drug Discovery of Liaoning Province, Shenyang Pharmaceutical University, Shenyang 110016, China. jiaxian206@163.com.

Physical chemistry chemical physics : PCCP
|August 26, 2025
PubMed
まとめ

SGLT1/ 2の類似性により,糖尿病に対する選択的ナトリウム- グルコース共輸送剤 (SGLT) 阻害剤の設計は困難である. 結合ポケットの空間的な補完性は,将来の薬剤設計を導く,阻害剤の選択性の鍵です.

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