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Updated: Jun 20, 2026

Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy
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Establishment of Human Epithelial Enteroids and Colonoids from Whole Tissue and Biopsy

Published on: March 6, 2015

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ヒトの外皮器官は,ディジョージ症候群の細胞起源を明らかにする

Ed Zandro M Taroc1, Surangi Perera1, Tunde Berecz1

  • 1Neural Crest Development and Disease Unit, National Institute of Dental and Craniofacial Research, Intramural Research Program, National Institutes of Health, Bethesda, USA.

bioRxiv : the preprint server for biology
|August 26, 2025
PubMed
まとめ

生まれつきの欠陥の主要な原因である神経結晶病は,新しい3Dオーガノイドモデルを使用して研究されています. このモデルはディジョージ症候群が 主にニューラル・クライスト障害であり 幹細胞から分化細胞への発達に 影響していることを示しています

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Establishing Organoids from Human Tooth as a Powerful Tool Toward Mechanistic Research and Regenerative Therapy11:02

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Cancers Originate from Somatic Mutations in a Single Cell

Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
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