ヒップと膝関節置換術後の静脈血栓栓症の管理

Alexander Postajian¹, Edgmin Rostomian¹, Alexander Abdou¹

¹Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, 91766, USA.

Journal of orthopaedics and sports medicine

|August 26, 2025

まとめ

静脈血栓塞栓症 (VTE) を予防することは極めて重要です. このレビューでは,全関節整形手術の患者のための薬剤や外科技術を含む,VTEのリスク要因,検出,予防戦略について検討しています.

科学分野:

整形術
血管医学
薬理学について

背景:

静脈血栓塞栓症 (VTE),深静脈血栓症 (DVT) と肺栓塞症 (PE) は,全関節整形手術 (THA) と全膝関節整形手術 (TKA) の後の死亡率の重要な原因である.
世界中でTHAとTKAの流行が増加しているため,静脈性腫瘍予防 (血栓予防) の最適化戦略が必要である.

研究の目的:

THAとTKA患者のVTEリスク因子,検出,予防に関する現在の文献をレビューする.
様々な薬理学的および機械的な血栓予防法の有効性と安全性を比較する.
手術の進歩がVTEのリスクに与える影響について議論する.

主な方法:

THAとTKAにおけるVTEに関する既存の文献の包括的なレビュー.
薬理学的薬剤の比較分析:アスピリン,低分子量ヘパリン,リバロキサバン,アピキサバン,ワーファリン
機械的な方法と手術中の要因の評価 (麻酔,手術の時間,帯の使用)
最低侵襲手術やロボットによる外科手術の探索

主要な成果:

VTEの予防には複数の薬理学的および機械的な介入があります.
最低侵襲手術やロボットによる手術も進化しています
単一の最適な血栓予防療法は普遍的に確立されていません.

結論:

THA と TKA の後の最適なVTE予防には,個々の患者の要因を考慮する必要があります.
パーソナライズされた血栓予防の戦略を洗練するためにさらなる研究が必要になる可能性があります.
静脈動脈突発症の予防と出血のリスクをバランス取ることは重要な課題です

キーワード:

深静脈血栓症最低侵襲手術薬学的な血栓予防肺栓塞ロボットによる手術整体股関節整形手術整体関節整形膝関節整形手術静脈血栓塞栓症

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