関連する実験動画

Updated: Sep 10, 2025

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry
14:47

Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

Published on: May 17, 2016

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JMJD6とYBX1は物理的に相互作用し,HOTAIR近接プロモーターを調節する

Aritra Gupta1,2, Siddharth Bhardwaj1, Kartiki V Desai1,2

  • 1Biotechnology Research Innovation Council-National Institute of Biomedical Genomics (BRIC-NIBMG), Kalyani, West Bengal, India.

The Biochemical journal
|August 26, 2025
PubMed
まとめ

Yボックス相互作用タンパク質1 (YBX1) は,HOTAIRプロモーターにタンパク質6 (JMJD6) を含んだジャンモニドメインを物理的に誘導し,腫瘍の進行を促します. この相互作用により,乳がんにおけるHOTAIR発現を高める ポジティブなフィードバックループが形成されます.

キーワード:
乳がんコイムノプレシピテーション遺伝子調節長い間隔のノンコーディングRNA

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