進行卵巣がんにおける術後の合併症に関連した臨床的に重要な液体バランスの値の見通し評価
PubMedで要約を見る
まとめ
この要約は機械生成です。進行卵巣がんの手術では 術後の液体バランスを最適化することが重要です 1750mL未満の液体バランスを維持すると,主要な術後の合併症が軽減され,アシテスは2700mL未満の目標値を示唆する.
科学分野
- アネステシオロジーと手術前医学
- 手術腫瘍学
- クリティカル ケア 医療
背景
- 細胞縮小手術を受けた進行卵巣がん患者の最適な手術前流体管理に関するデータは限られている.
- これらの患者はしばしば悪性アシテスを有し,重大な液体の変化を経験します.
- 手術後の重大な合併症を防ぐには 液体のバランスを理解することが重要です
研究 の 目的
- 最適な手術前流体バランスのための臨床目標を定義する.
- 初期アシテスが流体損失の計算に含まれるべきかどうかを判断する.
- 術後の液体バランスと 重大な術後の合併症との関連を調べる
主な方法
- 細胞縮小手術を受けた先進性卵巣がん患者162人を対象とした前向きな観察研究.
- 流体入力と出力を24時間にわたって測定した.
- 多変数回帰分析は,共変数調整により,流体バランスと主要な術後の合併症の関連性を評価した.
主要な成果
- 1750〜2700mL (OR3. 40),2700mL (OR3. 91) の液体バランスは,重度の術後の合併症と有意に関連していました.
- 流体損失の計算における初期アシテスを含めると,残留量> 2700 mLは合併症と関連していた (OR2. 59).
結論
- 大規模な術後の合併症の確率を下げるために,手術前流体バランスの目標値 < 1750 mL を推奨する.
- 流体バランスの計算に初期アシテスを含めると,2700mL未満の最適な目標値を示唆する.
- これらの結果は,この患者集団における流体管理を最適化するための実用的な基準値を提供します.
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