韓国における眼内圧と代謝症候群の危険因子の関連
Jun Young Lee1, Myung Ho Cho1, Jiwoong Lee1,2
1Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea.
Journal of Korean medical science
|August 26, 2025
まとめ
メタボリックシンドロームの危険因子,特に腹部肥満は,高眼圧 (IOP) と眼高血圧 (OHT) と関連しています. メタボリックシンドロームを患っている人にとって,定期的なIOPスクリーニングは,緑内障の進行を防ぐために極めて重要です.
科学分野:
- 眼科について
- 代謝 健康
- 公衆衛生
背景:
- 失明 の 主要 な 原因 と なっ て いる グラウコマ は,眼内 圧力 (IOP) の 上昇 と 関連 し て い ます.
- 代謝症候群は,肥満,高血圧,高血糖,脂質不全によって特徴付けられ,内血圧の上昇と関連しています.
- この研究では,韓国人の成人における代謝性シンドロームの危険因子と内血圧の関係を調べています.
研究 の 目的:
- メタボリックシンドロームの危険因子と眼内圧 (IOP) の関連性を調べる.
- 特定の代謝症候群の成分と眼高血圧 (OHT) の関係を決定する.
主な方法:
- 2021年の韓国国民健康栄養調査から1,896人の成人 (19~59歳) のデータを分析した.
- 緑内障,以前の眼科手術,または緑内障の薬の使用者を除外します.
- メタボリックシンドロームの危険因子 (血圧,グルコース,インスリン抵抗性,BMI,腹部肥満,トリグリセリド,HDL) とOHTの関連性を評価するために使用される多変量ロジスティック回帰.
主要な成果:
- メタボリックシンドロームの被験者は正常なグループより平均IOPが有意に高かった (16. 05対15. 33mmHg).
- ハイパーグリセミアとハイパートリグリセリデミアは,高血圧と有意に関連していた.
- 腹部肥満は,眼高血圧と強い関連性を示した (OR,2. 90; 95% CI,1. 35~6. 23).
結論:
- メタボリックシンドロームの危険因子,特に腹部肥満は,眼高血圧と有意に関連しています.
- メタボリックシンドロームの患者には,緑内障の進行リスクを軽減するために定期的なIOPスクリーニングが推奨されます.
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