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Updated: Sep 10, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions

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ヒストンデセチラーゼ阻害剤のヴォーリノスタットと炭酸アンヒドラゼIIおよびIXの非標的結合

Mitchell C Gulkis1, James T Hodgkinson2, Céleste P Sele3

  • 1Department of Biochemistry and Molecular Biology, University of Florida, 1149 Newell Drive, Gainesville, FL 32610, USA.

Acta crystallographica. Section F, Structural biology communications
|August 26, 2025
PubMed
まとめ

癌薬であるヴォリノスタット (SAHA) は,炭酸水素 (CA) に結合し,副作用を引き起こす可能性があります. この研究は,SAHA

キーワード:
HDAC 阻害剤SAHA について人間炭酸水素オフ・ターゲット・バインディングボリノスタット

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