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Updated: Jun 10, 2026

The Corneal Micropocket Assay: A Model of Angiogenesis in the Mouse Eye
11:49

The Corneal Micropocket Assay: A Model of Angiogenesis in the Mouse Eye

Published on: August 16, 2014

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高血糖症による血小板由来成長因子-BBの発現が減少し,糖尿病マウスの角膜創傷治癒を阻害する

Yangyang Zhang1,2, Rui Wang1,2,3, Ya Li2

  • 1Eye Institute of Shandong First Medical University, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, China.

Investigative ophthalmology & visual science
|August 26, 2025
PubMed
まとめ

血小板由来成長因子BB (PDGF-BB) を減少させ,角膜の治癒と神経修復を阻害する. PDGF-BBの補充は,ERK1/2とAKT経路による治癒を促進し,糖尿病性眼疾患の潜在的な治療法を提供します.

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Hormones Regulating Blood Glucose01:16

Hormones Regulating Blood Glucose

Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
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Pathophysiology of Diabetes

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Diabetic Retinopathy

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Diabetic Nephropathy01:28

Diabetic Nephropathy

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Diabetic Neuropathy

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