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Updated: Sep 10, 2025

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
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Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

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病気の進行後に積極的介入に移行する対照群の患者によるランダム化制御試験における全生存に対する治療効果に関する因果推論のための限界構造モデルの適用

Jing Xu1, Camden Bay1, Bingxia Wang1

  • 1Statistical and Quantitative Sciences, Takeda Development Center Americas, Inc., Cambridge, MA, USA.

Journal of biopharmaceutical statistics
|August 26, 2025
PubMed
まとめ

この研究は,一方向の治療の切り替えによるランダム化臨床試験 (RCT) で,限界構造モデル (MSM) を適用するための新しい2段階のアプローチを導入しています. この方法は,対照群が積極的介入に移行しても,生存に対する因果的な治療効果を正確に推定します.

キーワード:
逆確率の重み付け限界構造モデル片道処理の切り替え時間依存の混同トリートメントの切り替え

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