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Updated: Sep 10, 2025

Metabolic Labeling of Leucine Rich Repeat Kinases 1 and 2 with Radioactive Phosphate
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神経変性におけるロキナーゼイソフォーム:細胞機能から治療標的まで

Chesta Shandilya1, Shalini Mani2

  • 1Centre for Emerging Diseases, Department of Biotechnology, Jaypee Institute of Information Technology, Sector 62, Noida, A-10, 201301, UP, India.

Molecular biology reports
|August 26, 2025
PubMed
まとめ

ミトコンドリアの健康とニューロンの機能を改善することで,神経変性疾患 (NDD) の治療において,ロキナーゼ (ROCK) の同型をターゲットにすることが有望である. ROCK経路を阻害すると,パーキンソン病のような疾患に対する神経保護がもたらされる.

キーワード:
ミトコンドリア動態ミトファジー神経変性疾患神経保護剤ROCK アイソフォーム

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