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Updated: Sep 10, 2025

A Doxorubicin-induced Cardiomyopathy Model in Adult Zebrafish
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ドクソルビシン誘発性心臓毒性に対するSGLT2阻害剤のクラス効果

Jueqian Yan1,2, Ke Lin1, Shanshan Dai3

  • 1Key Laboratory of Cardiovascular Disease, Wenzhou, Department of Cardiology, First Affiliated Hospital of Wenzhou Medical University, Nanbaixiang, Wenzhou, Zhejiang, 325100, People's Republic of China.

Cardiovascular drugs and therapy
|August 26, 2025
PubMed
まとめ

SGLT2阻害剤はドクソルビシンによる心臓毒性の予防にクラス効果を発揮する. この保護は,アデノシンキナーゼ (ADK) を阻害することで媒介され,それによって酸化ストレスが軽減されます.

キーワード:
アデノシンキナーゼドクソルビシンによる心臓毒性酸化ストレスSGLT2阻害剤

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