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Updated: Sep 10, 2025

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SP1活性化されたCFL2は,高グルコース誘発の網膜色素上皮細胞損傷を促進し,AMPK/mTOR経路を関与させる

Jinan Xiao1, Jingni Yu1, Mei Ren1

  • 1Department of Ophthalmology, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an, China.

Journal of diabetes investigation
|August 26, 2025
PubMed
まとめ

コフィリン-2 (CFL2) は,SP1/AMPK/mTOR経路を通じて網膜の皮質細胞損傷を促進することによって,糖尿病性網膜症 (DR) を悪化させる. CFL2をターゲットにすることで DRの潜在的な治療戦略が提供されます.

キーワード:
CFL2 について糖尿病性網膜症網膜の皮質皮質細胞

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