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Updated: Sep 10, 2025

Bioluminescent Optogenetics 2.0: Harnessing Bioluminescence to Activate Photosensory Proteins In Vitro and In Vivo
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刺激に反応するルミノフォール駆動メカニズムスイッチ 高効率の電気化学発光免疫センシング

Alessandro Fracassa1, Giulia Ferrari2, Maria Vittoria Balli1

  • 1Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Piero Gobetti 85, 40129 Bologna, Italy.

Journal of the American Chemical Society
|August 26, 2025
PubMed
まとめ

研究者らは,電気化学発光 (ECL) 測定のための新しい刺激反応性ルミノフォアを開発した. このイノベーションにより,SARS-CoV-2のスパイクタンパク質検出のような重要な診断に対する感度が著しく向上します.

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Photoluminescence: Applications01:14

Photoluminescence: Applications

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...
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Immunofluorescence Microscopy

A fluorescence microscope uses fluorescent chromophores called fluorochromes, which can absorb energy from a light source and then emit this energy as visible light. Fluorochromes include naturally fluorescent substances (such as chlorophylls) and fluorescent stains that are added to the specimen to create contrast. Dyes such as Texas red and FITC are examples of fluorochromes. Other examples include the nucleic acid dyes 4’,6’-diamidino-2-phenylindole (DAPI), and acridine orange.
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