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Updated: Sep 10, 2025

Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays
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Published on: April 18, 2025

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NONOは,潜在的PI3K/AKT依存メカニズムを通じてモノサイトマクロファージの系統分化を調節する

Xiu-Rong Wei1, Dan Hu1, Zi-Jiang Yang1

  • 1Department of Physiology, Basic Medical School, Guangdong Medical University, Zhanjiang, China.

Differentiation; research in biological diversity
|August 26, 2025
PubMed
まとめ

オクターマー結合タンパク質 (NONO) を含む非POUドメインは,単細胞-マクロファージの分化を調節する. 減少したNONOはPI3K/AKT経路を通じてこのプロセスを強化し,免疫細胞の発達に関する洞察を提供します.

キーワード:
区分するマクロファージノノ ノノPI3K/AKT

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