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Updated: Sep 10, 2025

Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease
08:15

Author Spotlight: Network Pharmacology and Molecular Docking to Decipher the Action of Jiawei Shengjiang San Against Diabetic Kidney Disease

Published on: May 10, 2024

654

モンテカルロベースのQSARモデリング,分子ドッキング,ADMEプロファイリングを用いたエンドセリン受容体のシリコ設計

Marija Marinković1, Nemanja Nikolić2, Tamara Nikolić3

  • 1Pulmonology Clinic, University Clinical Center Niš, Niš, Serbia.

Journal of molecular graphics & modelling
|August 26, 2025
PubMed
まとめ

計算モデルにより,心臓血管疾患に対する新しいエンドセリン-1 (ET-1) 反抗剤が成功しました. この研究では,重要な分子断片を特定し,ドッキングとADMEプロファイリングを使用して新しい阻害剤を検証し,薬剤発見を加速しました.

キーワード:
薬剤設計エンドセリン-1分子モデリングQSAR について血管圧縮剤

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