ACAA2の乳化と発現は,フェニルフリン誘発の心筋細胞増殖におけるミトコンドリア機能障害を媒介する

Yingying Guo1, Meng Zhang2, Wanyi Li1

  • 1Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, PR China; Hubei Key Laboratory of Metabolic and Chronic Diseases, Wuhan, 430060, PR China.

まとめ

アチル-CoA受容体タンパク質2 (ACAA2) のダウンレギュレーションおよびその乳化により,ミトコンドリアの機能が低下することで,心臓の大幅化が悪化する. ACAA2の復元は 心不全の治療策となるかもしれません

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