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Updated: Sep 10, 2025

Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex
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Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex

Published on: February 25, 2022

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スパイクタイミング依存の可塑性の誘導後のシナプスの超構造分析

Rui Wang1, Michaela Schweizer2, Margarita Anisimova1

  • 1Institute for Synaptic Neuroscience, ZMNH, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.

Cell reports methods
|August 26, 2025
PubMed
まとめ

この研究は,光遺伝学と高度な顕微鏡を用いて,スパイクタイミング依存性可塑性 (STDP) 誘導後のシナプス変化を観察するための新しい方法を示しています. 研究者はヒポカンプスの刺激されたシナプスの超構造を 視覚化することに成功しました

キーワード:
CP: 神経科学軸索と脊椎のインターフェースチャネルロドプシンdAPEX2 についてデンドリット型脊椎電子顕微鏡ヒッポカンプス長期的な増強ポストシナプス密度スパイクタイミング依存の可塑性シナプスベシクル

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