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Updated: Sep 10, 2025

Preparation, Administration, and Assessment of In Vivo Tissue-Specific Cellular Uptake of Fluorescent Dye-Labeled Liposomes
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リポソームにおけるベルベリン分布のマッピング:局所化と放出における薬物-リン脂相互作用の役割

Namrata Dhakal1, Yan Cao2, Flavio Costa3

  • 1Department of Pharmacy, Faculty of Science, National University of Singapore, 4 Science Drive 2, 117544, Singapore.

International journal of pharmaceutics
|August 26, 2025
PubMed
まとめ

リポソーム内の薬物の局所化は,放出率に大きな影響を与えます. リポソーム内のDPPGのような高濃度の有電性脂質は,より速い膜浸透ではなく,表面吸収によるベルベリンの放出を加速する.

キーワード:
ベルベリン制御された放出薬物局所化脂質と薬物の相互作用リポソーム分子ダイナミクスシミュレーション

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