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Updated: Sep 10, 2025

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
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PTPN14/MARK3/Hippo信号軸を調節することによって,腫瘍増殖と進行をフェノフィブラート媒介で抑制する

Yang Liu1, Xuedi Cao1, Tengrui Zhang1

  • 1Center of Basic Medical Research, Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing 100191, China; Cancer Center of Peking University Third Hospital, Beijing 100191, China.

Pharmacological research
|August 26, 2025
PubMed
まとめ

フェノフィブラート (FF) はPTPN14を標的とし,Hippo経路を調節することで抗癌効果を示しています. この薬は化学療法を強化し 癌治療の新たな戦略を提示します

キーワード:
フェノフィブラート海馬非受容体チロシン・フォスファタゼ14信号経路ターゲット識別

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