妊娠前期に特異的なベンゾジアゼピン被曝に関連した早産と低出生体重のリスク

Vincent Chin-Hung Chen1, Yi-Lung Chen1, Kai-Liang Kao1

  • 1From the Department of Psychiatry, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan (V.C.-H. Chen); Department of Psychiatry, Chang Gung University, Taoyuan, Taiwan (V.C.-H. Chen); Department of Healthcare Administration, Asia University, Taichung, Taiwan (Y.-L. Chen); Department of Psychology, Asia University, Taichung, Taiwan (Y.-L. Chen); Department of Pediatrics, Far Eastern Memorial Hospital (Kao); School of Occupational Therapy, College of Medicine, National Taiwan University (Lee); Department of Psychiatry, Wan-Fang Hospital and School of Medicine, College of Medicine, Taipei Medical University (Lu); Department of Medicine, Mackay Medical College (Wu); Department of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan (Wu); Institute of Psychiatry, Psychology and Neuroscience, King's College London (Stewart); South London and Maudsley NHS Foundation Trust, London, UK (Stewart).

まとめ

妊娠3ヶ月間にベンゾジアゼピンを使用すると,早産 (PTB) と妊娠年齢 (SGA) の幼児のリスクが著しく増加します. 妊娠前半の被曝は,これらの有害な出産結果と有意な関連性を示さなかった.

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